About   Help   FAQ
Tour our new Quick Search
Stil Gene Detail
 Symbol
Name
ID
Stil
Scl/Tal1 interrupting locus
MGI:107477

Nomenclature History
Synonyms Sil
Genetic Map
Chromosome 4
Syntenic
 
Mapping data( 3)
Sequence Map
Chr4:114672764-114715801 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: human SIL protein
TreeFam: TF331178
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000008583 VEGA Gene Model | MGI Sequence Detail 43038 C57BL/6J ± Kb
transcript NM_009185 RefSeq | MGI Sequence Detail 5333 C57BL/6
polypeptide Q60988 UniProt | EBI | MGI Sequence Detail 1262 Not Applicable
For the selected sequences
All sequences(33)
Alleles
and
phenotypes 		All alleles(3) : Targeted, knock-out(1) Gene trapped(2)
Mice homozygous for disruptions in this gene die as embryos with various neural tube defects.
Polymorphisms SNPs within 2kb(286 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process determination of left/right symmetry, embryonic axis specification...
Component cytoplasm
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Assays (2)    Results (103)    Tissues (103)    Images (14)
Theiler Stages: 19,22,28
  Assay Type Assays   Results
      RNA in situ 1   93
      Northern blot 1   10
cDNA source data(65)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(68) cDNA(67) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000028718
DoTS DT.101734930, DT.102525872, DT.528461, DT.91321927
Consensus CDS Project CCDS18485.1
UniGene 3988
DFCI TC1580524, TC1612441, TC1623634, TC1643616
NIA Mouse Gene Index U004663, U004664
Entrez Gene 20460
VEGA Gene Model OTTMUSG00000008583
International Mouse Knockout Project Status Stil
References
(Earliest) J:30658 Aplan PD et al., "Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia." Mol Cell Biol 1991 Nov;11(11):5462-9
(Latest) J:100018 Campaner S et al., "Sil phosphorylation in a pin1 binding domain affects the duration of the spindle checkpoint." Mol Cell Biol 2005 Aug;25(15):6660-72
All references(12)
Other
accession IDs 		MGD-MRK-36044
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory