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Selplg Gene Detail
 Symbol
Name
ID
Selplg
selectin, platelet (p-selectin) ligand
MGI:106689


Nomenclature History
Synonyms CD162, Psgl-1, Psgl1
Genetic Map
Chromosome 5
64.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr5:114268561-114280442 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Selplg ± 2 cM)
TreeFam: TF337792
Sequences
Representative Sequences Length Strain/Species Flank
genomic 20345 NCBI Gene Model | MGI Sequence Detail 11882 C57BL/6J ± Kb
transcript NM_009151 RefSeq | MGI Sequence Detail 2604 C57BL/6
polypeptide Q62170 UniProt | EBI | MGI Sequence Detail 397 Not Applicable
For the selected sequences
All sequences(34)
Alleles
and
phenotypes
All alleles(3) : Targeted, knock-out(3)
Mice homozygous for a null allele exhibit neutrophillia and impaired leukocyte adhesion and rolling.
Polymorphisms RFLP(1) SNPs within 2kb(47 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(7)
Process cell adhesion, leukocyte tethering or rolling...
Component integral to membrane, membrane...
Function protein binding, sugar binding...
External Resources: MouseFunc
Expression Literature Summary: (1 records)
cDNA source data(39)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(40) Genomic(1) cDNA(39)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000048163
DoTS DT.101408875, DT.110695196, DT.40145623, DT.99864705
UniGene 332590
PDB 2EMT
DFCI TC1572763, TC1587911, TC1710127
NIA Mouse Gene Index U026593, U375907
Entrez Gene 20345
International Mouse Knockout Project Status Selplg
References
(Earliest) J:33106 Yang J et al., "Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor." Blood 1996 May 15;87(10):4176-86
(Latest) J:149370 Hidalgo A et al., "Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury." Nat Med 2009 Apr;15(4):384-91
All references(48)
Other
accession IDs
MGD-MRK-35148

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory