Symbol
Name
ID
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(31)
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Alleles
and
phenotypes
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All alleles(11) :
Gene trapped(6)
Spontaneous(3)
Chemically induced(2)
| Homozygous mutant mice exhibit deafness and related behavioral characteristics such as circling, head tossing and hyperactivity. Progressive degeneration of the cochlear hair cells and the organ of Corti is observed with one mutation. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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All PCR and RFLP(11) :
PCR(8)
RFLP(3)
SNPs within 2kb(1224 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (24 records)
Data Summary:
Assays (3)
Results (23)
Tissues (11)
Images (7)
Theiler Stages: 19,21,22,23,24,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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4 |
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Immunohistochemistry |
2 |
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19 |
cDNA source data(94)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(109)
Genomic(4)
cDNA(96)
Primer pair(6)
Other(3)
Antibodies(2)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR000048 |
IQ calmodulin-binding region |
| IPR001609 |
Myosin head, motor domain |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:26341
Dickie MM,
"New mutant - achondroplasia - cn"
Mouse News Lett 1960;23():34
(Latest)
J:153972
Roux I et al.,
"Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses."
Hum Mol Genet 2009 Dec 1;18(23):4615-28
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All references(65)
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Other
accession IDs
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MGD-MRK-14657, MGD-MRK-28077, MGI:2670991
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