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Mgat3 Gene Detail
 Symbol
Name
ID
Mgat3
mannoside acetylglucosaminyltransferase 3
MGI:104532


Nomenclature History
Synonyms 1110038J12Rik, GnT-III
Genetic Map
Chromosome 15
46.2 cM, cytoband E
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr15:80004151-80045949 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Mgat3 ± 2 cM)
TreeFam: TF323781
Sequences
Representative Sequences Length Strain/Species Flank
genomic 17309 NCBI Gene Model | MGI Sequence Detail 41799 C57BL/6J ± Kb
transcript NM_010795 RefSeq | MGI Sequence Detail 4665 -
polypeptide Q10470 UniProt | EBI | MGI Sequence Detail 538 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes
All alleles(6) : Targeted, knock-out(2) Gene trapped(4)
Mice homozygous for a null allele exhibit reduced DEN and PB-induced hepatic tumors and reduced hepatocyte proliferation.
Polymorphisms RFLP(1) SNPs within 2kb(199 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process protein amino acid N-linked glycosylation
Component Golgi apparatus, integral to membrane...
Function beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity, transferase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (5)    Results (23)    Tissues (12)    Images (4)
Theiler Stages: 15,17,19,22,23,24,25,26,28
  Assay Type Assays   Results
      Western blot 2   3
      RNA in situ 1   1
      Northern blot 2   19
cDNA source data(64)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(70) Genomic(6) cDNA(64) Antibodies(1)
Microarray probesets(2)
Other database
links
EC 2.4.1.144
Ensembl Gene Model ENSMUSG00000042428
DoTS DT.40176877
Consensus CDS Project CCDS27660.1
UniGene 299693
DFCI TC1597065, TC1652371
NIA Mouse Gene Index U016444
Entrez Gene 17309
International Mouse Knockout Project Status Mgat3
Protein
domains
InterPro ID Description
IPR006813 Glycosyl transferase, family 17
Graphical View of Protein Domain Structure
References
(Earliest) J:29635 Bhaumik M et al., "Cloning and chromosomal mapping of the mouse Mgat3 gene encoding N-acetylglucosaminyltransferase III." Gene 1995 Oct 27;164(2):295-300
(Latest) J:116904 Nogaki F et al., "Chromosomal mapping of hyperserum IgA and glomerular IgA deposition in a high IgA (HIGA) strain of DdY mice." Kidney Int 2005 Dec;68(6):2517-25
All references(13)
Other
accession IDs
MGD-MRK-25963, MGI:1916016, MGI:2146079

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory