Symbol
Name
ID
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(37)
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Alleles
and
phenotypes
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All alleles(2) :
Targeted, knock-out(1)
Targeted, other(1)
| Mice homozygous for disruptions in this gene display some degree of pre- or postnatal lethality. Surviving adults for one allele appear to be normal. Heterozygous females for one allele display decreased depression related behaviors. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(387 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (9 records)
Data Summary:
Assays (7)
Results (238)
Tissues (166)
Images (15)
Theiler Stages: 22,23,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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38 |
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In situ reporter (knock in) |
1 |
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30 |
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RNA in situ |
4 |
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150 |
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Northern blot |
1 |
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20 |
cDNA source data(86)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(92)
cDNA(88)
Primer pair(2)
Other(2)
Microarray probesets(3)
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Pathways
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR001054 |
Adenylyl cyclase class-3/4/guanylyl cyclase |
| IPR009398 |
Adenylate cyclase-like |
| IPR018297 |
Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:21500
Watson PA et al.,
"Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells."
J Biol Chem 1994 Nov 18;269(46):28893-8
(Latest)
J:141439
Kaya F et al.,
"Ascorbic acid is a regulator of the intracellular cAMP concentration: old molecule, new functions?"
FEBS Lett 2008 Oct 29;582(25-26):3614-8
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All references(17)
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Other
accession IDs
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MGD-MRK-23725, MGI:2142399
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