Symbol
Name
ID
|
|
|
Synonyms
|
AC3, mKIAA0511
|
|
Genetic Map
|
|
Chromosome 12
|
cytoband A-B
|
|
|
|
Mapping data(
1)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(24)
|
Alleles
and
phenotypes
|
All alleles(7) :
Targeted, knock-out(1)
Targeted, other(1)
Gene trapped(5)
| Mice homozygous for one mutation of this gene display impaired olfaction and disorganization of glomeruli in the main olfactory bulb. Mutant animals also appear to be sterile as homozygous matings failed to produce litters. Mice with another mutant allele fail to survive beyond weaning. |
|
|
Polymorphisms
|
SNPs within 2kb(248 from dbSNP Build 128)
SNPs within 2kb including multiple locations(250)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (17 records)
Data Summary:
Assays (7)
Results (357)
Tissues (182)
Images (48)
Theiler Stages: 22,23,24,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
38 |
| |
In situ reporter (knock in) |
1 |
|
66 |
| |
RNA in situ |
5 |
|
253 |
cDNA source data(30)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(34)
cDNA(31)
Primer pair(2)
Other(1)
Microarray probesets(3)
|
|
Pathways
|
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001054 |
Adenylyl cyclase class-3/4/guanylyl cyclase |
| IPR018297 |
Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:22804
Edelhoff S et al.,
"Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse."
Mamm Genome 1995 Feb;6(2):111-3
(Latest)
J:153623
Wang Z et al.,
"Adult type 3 adenylyl cyclase-deficient mice are obese."
PLoS One 2009;4(9):e6979
|
All references(32)
|
Other
accession IDs
|
MGD-MRK-16460
|
