Symbol
Name
ID
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Synonyms
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tw, Wnt-7a
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(16)
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Alleles
and
phenotypes
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All alleles(6) :
Targeted, knock-out(1)
Gene trapped(2)
Spontaneous(2)
Chemically induced(1)
| Homozygous mutants have skeletal abnormalities including absence of digits, especially of the forelimb, and sometimes absence of the ulna. Occasionally, there is an extra set of ribs. Both sexes are sterile due to abnormalities of the Mullerian duct. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(279 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (88 records)
Data Summary:
Assays (24)
Results (383)
Tissues (219)
Images (66)
Theiler Stages: 1,2,3,4,5,8,9,11,13,14,15,16,17,18,19,20,22,23,24,26,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
|
1 |
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RT-PCR |
9 |
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79 |
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RNA in situ |
12 |
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296 |
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Immunohistochemistry |
1 |
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5 |
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RNase protection |
1 |
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2 |
cDNA source data(11)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(30)
Genomic(1)
cDNA(14)
Primer pair(12)
Other(3)
Antibodies(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:15022
Russell LB,
"HR - tw legs"
Mouse News Lett 1957;17():84
(Latest)
J:152705
Cohen ED et al.,
"Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway."
J Clin Invest 2009 Sep;119(9):2538-49
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All references(125)
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Other
accession IDs
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MGD-MRK-13698, MGD-MRK-15446, MGD-MRK-15456, MGD-MRK-35364, MGI:2141500, MGI:97825
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