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St3gal1 Gene Detail
 Symbol
Name
ID
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
MGI:98304


Nomenclature History
Synonyms CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase, Siat4, Siat4a, ST3GalI
Genetic Map
Chromosome 15
Syntenic
 
Mapping data( 3)
Sequence Map
Chr15:66934437-67008392 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; pig, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: sialyltransferase
TreeFam: TF354325
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000013846 Ensembl Gene Model | MGI Sequence Detail 73956 C57BL/6J ± Kb
transcript NM_009177 RefSeq | MGI Sequence Detail 5784 C57BL/6
polypeptide P54751 UniProt | EBI | MGI Sequence Detail 337 Not Applicable
For the selected sequences
All sequences(44)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Homozygous mutation of this gene results in altered terminal glycosylation.
Polymorphisms SNPs within 2kb(389 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(10)
Process protein amino acid glycosylation
Component extracellular region, Golgi apparatus...
Function beta-galactoside alpha-2,3-sialyltransferase activity, sialyltransferase activity...
External Resources: MouseFunc
Expression Literature Summary: (3 records)
Data Summary: Assays (2)    Results (40)    Tissues (15)
Theiler Stages: 12,22,28
  Assay Type Assays   Results
      RT-PCR 1   13
      Northern blot 1   27
cDNA source data(16)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(2)
Other database
links
EC 2.4.99.4
Ensembl Gene Model ENSMUSG00000013846
DoTS DT.101328938, DT.101343467, DT.101735143, DT.40154144, DT.94294864, DT.97353171
DFCI TC1581575, TC1584412, TC1602766, TC1613075, TC1625804, TC1627462, TC1634028, TC1671763
NIA Mouse Gene Index U036247
Entrez Gene 20442
International Mouse Knockout Project Status St3gal1
Protein
domains
InterPro ID Description
IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
Graphical View of Protein Domain Structure
References
(Earliest) J:14675 Lee YC et al., "Molecular cloning and expression of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase from mouse brain." Eur J Biochem 1993 Sep 1;216(2):377-85
(Latest) J:118162 Van Dyken SJ et al., "Structural and mechanistic features of protein O glycosylation linked to CD8+ T-cell apoptosis." Mol Cell Biol 2007 Feb;27(3):1096-111
All references(14)
Other
accession IDs
MGD-MRK-14411, MGI:2146025

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory