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Npr3 Gene Detail
 Symbol
Name
ID
Npr3
natriuretic peptide receptor 3
MGI:97373


Nomenclature History
Synonyms B430320C24Rik, lgj, longjohn, Nppc receptor, NPR-C
Genetic Map
Chromosome 15
6.7 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 8)

Sequence Map
Chr15:11769651-11835429 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Npr3 ± 2 cM)
Protein SuperFamily: natriuretic peptide receptor C
TreeFam: TF106339
Sequences
Representative Sequences Length Strain/Species Flank
genomic 18162 NCBI Gene Model | MGI Sequence Detail 65779 C57BL/6J ± Kb
transcript NM_008728 RefSeq | MGI Sequence Detail 6927 C57BL/6
polypeptide P70180 UniProt | EBI | MGI Sequence Detail 536 Not Applicable
For the selected sequences
All sequences(34)
Alleles
and
phenotypes
All alleles(7) : Targeted, knock-out(1) Spontaneous(4) Chemically induced(2)
Phenotype Images (5)  
Polymorphisms RFLP(1) SNPs within 2kb(364 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(6)
Component integral to membrane, membrane...
Function chloride ion binding, peptide receptor activity, G-protein coupled...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (5)    Results (49)    Tissues (45)    Images (17)
Theiler Stages: 10,17,18,19,20,22,23,25,28
  Assay Type Assays   Results
      RNA in situ 3   37
      Northern blot 2   12
cDNA source data(17)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(23) Genomic(2) cDNA(18) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000022206
Entrez Gene 18162
International Mouse Knockout Project Status Npr3
Protein
domains
InterPro ID Description
IPR001170 Natriuretic peptide receptor, N-terminal
IPR001828 Extracellular ligand-binding receptor
Graphical View of Protein Domain Structure
References
(Earliest) J:34286 Levin ER et al., "Natriuretic peptides inhibit rat astroglial proliferation: mediation by C receptor." Am J Physiol 1991 Aug;261(2 Pt 2):R453-7
(Latest) J:152211 Coulpier F et al., "Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers." Glia 2009 Oct;57(13):1450-7
All references(22)
Other
accession IDs
MGD-MRK-12927, MGI:1330807, MGI:1330847, MGI:2146299, MGI:2442945

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory