About   Help   FAQ
Tour our new Quick Search
Clec10a Gene Detail
 Symbol
Name
ID
Clec10a
C-type lectin domain family 10, member A
MGI:96975

Nomenclature History
Synonyms CD301a, Mgl1
Genetic Map
Chromosome 11
37.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr11:69980125-69984336 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Clec10a ± 2 cM)
Protein SuperFamily: asialoglycoprotein receptor 1-like protein
TreeFam: TF352155
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000006033 VEGA Gene Model | MGI Sequence Detail 4212 C57BL/6J ± Kb
transcript NM_010796 RefSeq | MGI Sequence Detail 1345 C57BL/6
polypeptide P49300 UniProt | EBI | MGI Sequence Detail 304 Not Applicable
For the selected sequences
All sequences(21)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Homozygotes for a targeted null mutation exhibit elevated red blood cell counts but appear to be otherwise normal.
Polymorphisms RFLP(1) SNPs within 2kb(62 from dbSNP Build 128)   SNPs within 2kb including multiple locations(72)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component integral to membrane, membrane...
Function binding, calcium ion binding...
External Resources: FuncBase
Expression Literature Summary: (2 records)
cDNA source data(25)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(27) Genomic(1) cDNA(26)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000000318
DoTS DT.101364327, DT.94258450
Consensus CDS Project CCDS24936.1
UniGene 252405
DFCI TC1585536
NIA Mouse Gene Index U012846
Entrez Gene 17312
VEGA Gene Model OTTMUSG00000006033
International Mouse Knockout Project Status Clec10a
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR002353 Type II antifreeze protein
IPR005640 Hepatic lectin, N-terminal
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:5439 Bannerman RM et al., "Hereditary disorders of the red cell in animals." Prog Hematol 1973;8():131-79
(Latest) J:155676 Westcott DJ et al., "MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity." J Exp Med 2009 Dec 21;206(13):3143-56
All references(17)
Other
accession IDs 		MGD-MRK-12220
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory