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Mag Gene Detail
 Symbol
Name
ID
Mag
myelin-associated glycoprotein
MGI:96912


Nomenclature History
Synonyms Gma, siglec-4a
Genetic Map
Chromosome 7
11.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 30)

Sequence Map
Chr7:31684202-31699851 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Mag ± 2 cM)
Protein SuperFamily: myelin-associated glycoprotein
TreeFam: TF332441
Sequences
Representative Sequences Length Strain/Species Flank
genomic 17136 NCBI Gene Model | MGI Sequence Detail 15650 C57BL/6J ± Kb
transcript NM_010758 RefSeq | MGI Sequence Detail 2427 C57BL/6
polypeptide P20917 UniProt | EBI | MGI Sequence Detail 626 Not Applicable
For the selected sequences
All sequences(38)
Alleles
and
phenotypes
All alleles(3) : Targeted, knock-out(3)
Homozygotes for targeted null mutations exhibit delayed CNS myelination, late myelin degeneration in peripheral nerves, hypomyelination of optic nerves, and subtle intention tremors.
Polymorphisms RFLP(4) SNPs within 2kb(85 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(6)
Process cell adhesion
Component integral to membrane, membrane...
Function protein binding, sugar binding...
External Resources: MouseFunc
Expression Literature Summary: (24 records)
Data Summary: Assays (4)    Results (51)    Tissues (47)    Images (3)
Theiler Stages: 23,28
  Assay Type Assays   Results
      RT-PCR 2   48
      RNA in situ 1   1
      Immunohistochemistry 1   2
cDNA source data(13)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(29) Genomic(7) cDNA(18) Primer pair(3) Other(1) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000036634
DoTS DT.101366368, DT.526835, DT.99856277
UniGene 241355
DFCI TC1581023, TC1606820
NIA Mouse Gene Index U028404
Entrez Gene 17136
International Mouse Knockout Project Status Mag
Protein
domains
InterPro ID Description
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set
IPR013783 Immunoglobulin-like fold
Graphical View of Protein Domain Structure
References
(Earliest) J:31033 Gilman AG, "G proteins and dual control of adenylate cyclase." Cell 1984 Mar;36(3):577-9
(Latest) J:144847 Nguyen T et al., "Axonal protective effects of the myelin-associated glycoprotein." J Neurosci 2009 Jan 21;29(3):630-7
All references(107)
Other
accession IDs
MGD-MRK-10172, MGD-MRK-12105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory