Symbol
Name
ID
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Synonyms
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Gma, siglec-4a
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(38)
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Alleles and phenotypes
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All alleles(3) :
Targeted, knock-out(3)
| Homozygotes for targeted null mutations exhibit delayed CNS myelination, late myelin degeneration in peripheral nerves, hypomyelination of optic nerves, and subtle intention tremors. |
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Polymorphisms
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RFLP(4)
SNPs within 2kb(85 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (26 records)
Data Summary:
Assays (4)
Results (51)
Tissues (47)
Images (3)
Theiler Stages: 23,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
2 |
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48 |
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RNA in situ |
1 |
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1 |
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Immunohistochemistry |
1 |
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2 |
cDNA source data(17)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular reagents
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All nucleic(33)
Genomic(7)
cDNA(22)
Primer pair(3)
Other(1)
Antibodies(1)
Microarray probesets(2)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:31033
Gilman AG,
"G proteins and dual control of adenylate cyclase."
Cell 1984 Mar;36(3):577-9
(Latest)
J:154660
Zhang Y et al.,
"Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination."
Proc Natl Acad Sci U S A 2009 Nov 10;106(45):19162-7
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All references(110)
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Other accession IDs
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MGD-MRK-10172, MGD-MRK-12105
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