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Lgals3 Gene Detail
 Symbol
Name
ID
Lgals3
lectin, galactose binding, soluble 3
MGI:96778


Nomenclature History
Synonyms gal3, galectin-3, L-34, Mac-2
Genetic Map
Chromosome 14
cytoband C1
 
Mapping data( 2)
Sequence Map
Chr14:47987426-48005835 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: galectin 3
TreeFam: TF315551
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000032779 VEGA Gene Model | MGI Sequence Detail 18410 C57BL/6J ± Kb
transcript NM_001145953 RefSeq | MGI Sequence Detail 1406 C57BL/6
polypeptide P16110 UniProt | EBI | MGI Sequence Detail 264 Not Applicable
For the selected sequences
All sequences(36)
Alleles
and
phenotypes
All alleles(16) : Targeted, knock-out(2) Gene trapped(14)
Polymorphisms SNPs within 2kb(132 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell differentiation, extracellular matrix organization...
Component cytoplasm, nucleus...
Function IgE binding, protein binding...
External Resources: FuncBase
Expression Literature Summary: (14 records)
Data Summary: Assays (3)    Results (57)    Tissues (42)    Images (14)
Theiler Stages: 11,13,14,15,19,20,21,22,23,28
  Assay Type Assays   Results
      RT-PCR 1   8
      RNA in situ 1   44
      Immunohistochemistry 1   5
cDNA source data(301)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(307) Genomic(5) cDNA(301) Primer pair(1) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000050335
DoTS DT.101356782, DT.110765552, DT.496319, DT.91447814, DT.97335310
Consensus CDS Project CCDS26986.1
UniGene 248615
DFCI TC1572166
NIA Mouse Gene Index U056994
Entrez Gene 16854
VEGA Gene Model OTTMUSG00000032779
International Mouse Knockout Project Status Lgals3
Protein
domains
InterPro ID Description
IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanase
IPR013320 Concanavalin A-like lectin/glucanase, subgroup
IPR015534 Galectin-3
Graphical View of Protein Domain Structure
References
(Earliest) J:17163 Jia S et al., "Carbohydrate binding protein 35. Complementary DNA sequence reveals homology with proteins of the heterogeneous nuclear RNP." J Biol Chem 1988 May 5;263(13):6009-11
(Latest) J:155503 Van den Bossche J et al., "Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes." Blood 2009 Nov 19;114(21):4664-74
All references(72)
Other
accession IDs
MGD-MRK-11797

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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