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Lgals1 Gene Detail
 Symbol
Name
ID
Lgals1
lectin, galactose binding, soluble 1
MGI:96777


Nomenclature History
Synonyms Gal-1, Galbp, galectin-1, L14, Lect14
Genetic Map
Chromosome 15
44.9 cM, cytoband E
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr15:78757172-78760622 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat; sheep    (Mammalian Orthology)
Comparative Map (Mouse/Human Lgals1 ± 2 cM)
Protein SuperFamily: beta-galactoside-binding lectin
TreeFam: TF315551
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000068220 Ensembl Gene Model | MGI Sequence Detail 3451 C57BL/6J ± Kb
transcript NM_008495 RefSeq | MGI Sequence Detail 817 C57BL/6
polypeptide P16045 UniProt | EBI | MGI Sequence Detail 135 Not Applicable
For the selected sequences
All sequences(28)
Alleles
and
phenotypes
All alleles(56) : Targeted, knock-out(1) Gene trapped(55)
Mice homozygous for disruptions in this gene are essentially normal and fertile.
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(38 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process heterophilic cell adhesion, myoblast differentiation...
Component extracellular region, extracellular space...
Function galactose binding, galactoside binding...
External Resources: MouseFunc
Expression Literature Summary: (16 records)
Data Summary: Assays (2)    Results (5)    Tissues (3)    Images (2)
Theiler Stages: 13,22
  Assay Type Assays   Results
      RT-PCR 1   4
      RNA in situ 1   1
cDNA source data(309)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents
All nucleic(316) Genomic(3) cDNA(310) Primer pair(2) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000068220
DoTS DT.101187054, DT.496470, DT.97387089
UniGene 43831
DFCI TC1573420
NIA Mouse Gene Index U016412
Entrez Gene 16852
International Mouse Knockout Project Status Lgals1
Protein
domains
InterPro ID Description
IPR001079 Galectin, carbohydrate recognition domain
IPR013320 Concanavalin A-like lectin/glucanase, subgroup
IPR015535 Galectin-1
Graphical View of Protein Domain Structure
References
(Earliest) J:113709 Gitt MA et al., "Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes." Proc Natl Acad Sci U S A 1986 Oct;83(20):7603-7
(Latest) J:153078 Shoji H et al., "Expression pattern and role of Galectin1 during early mouse myogenesis." Dev Growth Differ 2009 Sep;51(7):607-15
All references(54)
Other
accession IDs
MGD-MRK-11781, MGD-MRK-11796, MGD-MRK-9961, MGI:2145905

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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