Symbol
Name
ID
|
|
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Synonyms
|
bHLHb25, HLH462, Idb3
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(36)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(2)
Gene trapped(2)
| Homozygotes for a targeted null mutation exhibit compromised humoral immunity. Homozygotes for knockout alleles of both Id1 and Id3 die by embryonic day 13.5 with vascular malformations of the forebrain. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(14 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (37 records)
Data Summary:
Assays (13)
Results (120)
Tissues (92)
Images (9)
Theiler Stages: 2,3,4,5,15,16,17,18,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
5 |
|
40 |
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RNA in situ |
5 |
|
58 |
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Immunohistochemistry |
1 |
|
3 |
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Northern blot |
2 |
|
19 |
cDNA source data(183)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
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All nucleic(194)
Genomic(2)
cDNA(186)
Primer pair(4)
Other(2)
Antibodies(1)
Microarray probesets(2)
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR001092 |
Helix-loop-helix DNA-binding domain |
| IPR011598 |
Helix-loop-helix DNA-binding |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:13202
Christy BA et al.,
"An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene."
Proc Natl Acad Sci U S A 1991 Mar 1;88(5):1815-9
(Latest)
J:153805
Lauritsen JP et al.,
"Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent."
Immunity 2009 Oct 16;31(4):565-75
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All references(80)
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Other
accession IDs
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MGD-MRK-11155
|
