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| Nomenclature |
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Symbol:
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Bap1tm1.1Geno
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Name:
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Brca1 associated protein 1;
targeted mutation 1.1, Genoway
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MGI ID: |
MGI:5439652 |
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Synonyms: |
Bap1fl |
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Gene:
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Bap1
Location:
Chr14:31251489-31259929 bp, + strand
Genetic Position: Chr14,
19.09 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:187380
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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C57BL/6
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:187380)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Bap1 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:187380
Dey A et al.,
"Loss of the tumor suppressor BAP1 causes myeloid transformation."
Science 2012 Sep 21;337(6101):1541-6
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All: |
1 reference(s)
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Analysis Tools
