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| Nomenclature |
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Symbol:
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CasrBCH011
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Name:
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calcium-sensing receptor;
bone calcium high mutant 011
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MGI ID: |
MGI:5424983 |
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Gene:
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Casr
Location:
Chr16:36493696-36562141 bp, - strand
Genetic Position: Chr16,
25.57 cM
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Mutation
origin |
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Strain of Origin:
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C3HeB/FeJ
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This ENU-induced mutation was isolated in a screen for metabolic bone disease as part of the Munich ENU Mutagenesis Project. Nonsense mutation in exon 7 of the gene, a C-to-T point mutation at position 2017 of the cDNA is predicted to alter codon 673 in the encoded protein from a glutamine to a stop codon. (J:183993)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Casr Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:183993
Sabrautzki S et al.,
"New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis."
Mamm Genome 2012 Aug;23(7-8):416-30
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All: |
1 reference(s)
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Analysis Tools
