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| Nomenclature |
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Symbol:
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Tg(tetO-ATXN1*82Q)#Horr
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Name:
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transgene insertion, Harry T Orr
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MGI ID: |
MGI:5317077 |
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Synonyms: |
TRE-SCA1[82Q] |
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Transgene:
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Tg(tetO-ATXN1*82Q)#Horr
Location:
unknown
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Transgene origin |
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of the human ATXN1 (SCA1) cDNA encoding a mutant polyglutamine tract with 82 repeats joined to the TRE element. Seven founders were generated and the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:95453)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:95453
Zu T et al.,
"Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice."
J Neurosci 2004 Oct 6;24(40):8853-61
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All: |
2 reference(s)
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