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| Nomenclature |
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Symbol:
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Kdm8tm1.2Tasu
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Name:
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lysine (K)-specific demethylase 8;
targeted mutation 1.2, Takeshi Suzuki
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MGI ID: |
MGI:5311834 |
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Synonyms: |
Jmjd5delta |
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Gene:
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Kdm8
Location:
Chr7:125444676-125462265 bp, + strand
Genetic Position: Chr7,
68.85 cM, cytoband F3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:181189
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Parent Cell Line:
| v6.5 (ES Cell) |
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Strain of Origin:
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(C57BL/6 x 129S4/SvJae)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A loxP site was inserted upstream of exon 4 and an FRT flanked inverted neo cassette and second loxP site were inserted downstream of exon 4 via homologous recombination. Flp and cre mediated recombination removed the neo cassette and exon 4. (J:181189)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Kdm8 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:181189
Ishimura A et al.,
"Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression."
Development 2012 Feb;139(4):749-59
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All: |
1 reference(s)
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Analysis Tools
