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| Nomenclature |
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Symbol:
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Tg(Lgi1*)#Mpan
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Name:
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transgene insertion, Matthew P Anderson
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MGI ID: |
MGI:5307228 |
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Synonyms: |
mLGI1 |
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Transgene:
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Tg(Lgi1*)#Mpan
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene consists of a hemagglutinin-tagged mouse Lgi1 BAC construct containing a premature translational stop codon in exon 6 to reproduce the human autosomal dominant lateral temporal lobe epilepsy mutation 835delC that truncates the C-terminal epitempin repeat and ADAM22-binding domain. (J:154129)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:154129
Zhou YD et al.,
"Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy."
Nat Med 2009 Oct;15(10):1208-14
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All: |
3 reference(s)
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Analysis Tools
