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| Nomenclature |
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Symbol:
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Cdkn1ctm2.1Kei
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Name:
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cyclin-dependent kinase inhibitor 1C (P57);
targeted mutation 2.1, Keiichi I Nakayama
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MGI ID: |
MGI:5294426 |
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Synonyms: |
p57Flox |
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Gene:
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Cdkn1c
Location:
Chr7:143458350-143461050 bp, - strand
Genetic Position: Chr7,
88.22 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:176209
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 2. A floxed neo cassette was inserted downstream of exon 4. Cre-mediated recombination removed the neo cassette and left exons 2 through 4 floxed. (J:176209)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cdkn1c Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:176209
Matsumoto A et al.,
"p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells."
Cell Stem Cell 2011 Sep 2;9(3):262-71
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All: |
3 reference(s)
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Analysis Tools
