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| Nomenclature |
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Symbol:
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Tg(ACTB-Fig4*I41T)705Mm
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Name:
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transgene insertion 705, Miriam H Meisler
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MGI ID: |
MGI:5014487 |
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Synonyms: |
FIG4-I41T, Tg705 |
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Transgene:
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Tg(ACTB-Fig4*I41T)705Mm
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6J x SJL)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A chicken beta-actin promoter drives expression of a mouse Fig4 cDNA carrying an I41T mutation. This line carries 4 copies of the transgene. Expression levels of Fig4 transcripts were increased 3 fold over non-transgenic controls. (J:173446)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:173446
Lenk GM et al.,
"Pathogenic Mechanism of the FIG4 Mutation Responsible for Charcot-Marie-Tooth Disease CMT4J."
PLoS Genet 2011 Jun;7(6):e1002104
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All: |
2 reference(s)
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Analysis Tools
