|
|
| Nomenclature |
|
Symbol:
|
Abl1tm2.1Goff
|
|
Name:
|
c-abl oncogene 1, non-receptor tyrosine kinase;
targeted mutation 2.1, Stephen P Goff
|
|
MGI ID: |
MGI:4850040 |
|
Synonyms: |
AblF |
|
Gene:
|
Abl1
Location:
Chr2:31688376-31804227 bp, + strand
Genetic Position: Chr2,
21.86 cM, cytoband B
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:166211
|
|
Parent Cell Line:
| E14 (ES Cell) |
|
Strain of Origin:
|
129P2/OlaHsd
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A loxP site was inserted at the end of intron 4 and a neo cassette flanked by two loxP sites were inserted into the middle of intron 6. The neo cassette was deleted by transiently transfection of an expression vector of Cre recombinase in the ES cells. Two independent heterozygous ES cell clones.
(J:166211)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:166211
Qiu Z et al.,
"Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum."
J Neurosci 2010 Oct 27;30(43):14430-9
|
|
All: |
1 reference(s)
|
|
Analysis Tools
