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| Nomenclature |
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Symbol:
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Tg(Camk2a-Tardbp)#Ckjs
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Name:
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transgene insertion, C K James Shen
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MGI ID: |
MGI:4830510 |
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Synonyms: |
CaMKII-TDP-43 |
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Transgene:
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Tg(Camk2a-Tardbp)#Ckjs
Location:
unknown
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Transgene origin |
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The mouse promoter drives expression of the full-legth cDNA in the cortex and hippocampus. Three lines were generated (# denotes line number not specified). (J:163612)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:163612
Tsai KJ et al.,
"Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U."
J Exp Med 2010 Aug 2;207(8):1661-73
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All: |
2 reference(s)
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