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| Nomenclature |
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Symbol:
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Irf6clft1
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Name:
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interferon regulatory factor 6;
cleft palate 1
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MGI ID: |
MGI:4457055 |
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Gene:
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Irf6
Location:
Chr1:193153112-193172042 bp, + strand
Genetic Position: Chr1,
97.6 cM
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Irf6clft1/Irf6clft1 palatal defects
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: ENU mutagenesis induced a C to T transition that results in the amino acid substitution of lysine for proline at position 39 (P39K). This allele is hypomorphic. (J:160190)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:160190
Stottmann RW et al.,
"Identification of a Van der Woude syndrome mutation in the cleft palate 1 mutant mouse."
Genesis 2010 May;48(5):303-8
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All: |
2 reference(s)
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Analysis Tools
