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| Nomenclature |
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Symbol:
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Mid1tm1Mero
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Name:
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midline 1;
targeted mutation 1, Germana Meroni
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MGI ID: |
MGI:4437430 |
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Gene:
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Mid1
Location:
ChrX:169685199-169990798 bp, + strand
Genetic Position: ChrX,
79.19 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:157828
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A fragment of the first coding exon including the first ATG was replaced with a neo selection cassette. RT-PCR and immunoblot analysis show the complete absence of the transcript and protein in embryos and adult brains, respectively. (J:157828)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:157828
Lancioni A et al.,
"Lack of Mid1, the mouse ortholog of the Opitz syndrome gene, causes abnormal development of the anterior cerebellar vermis."
J Neurosci 2010 Feb 24;30(8):2880-7
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All: |
1 reference(s)
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Analysis Tools
