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| Nomenclature |
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Symbol:
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Nr4a2tm2.1Tpe
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Name:
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nuclear receptor subfamily 4, group A, member 2;
targeted mutation 2.1, Thomas Perlmann
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MGI ID: |
MGI:4437024 |
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Synonyms: |
Nurr1L2 |
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Gene:
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Nr4a2
Location:
Chr2:57106830-57124003 bp, - strand
Genetic Position: Chr2,
31.66 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:157098
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 3. Cre mediated recombination removed the neo cassette leaving exon 3 floxed. (J:157098)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nr4a2 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:157098
Kadkhodaei B et al.,
"Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons."
J Neurosci 2009 Dec 16;29(50):15923-32
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All: |
3 reference(s)
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