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| Nomenclature |
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Symbol:
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Tg(tetO-SNCA*A53T)E2Cai
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Name:
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transgene insertion E2, Huaibin Cai
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MGI ID: |
MGI:4420801 |
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Synonyms: |
alpha-syn A53T, tetO-A53T |
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Transgene:
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Tg(tetO-SNCA*A53T)E2Cai
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6J
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A transgenic vector was generated encoding a human SNCA*A53T mutant gene under control of a tetO promoter. The construct was microinjected into C57BL/6J fertilized oocytes, and founder mice were bred to C57BL/6J mice to establish the E2 line. (J:156512)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:156512
Lin X et al.,
"Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein."
Neuron 2009 Dec 24;64(6):807-27
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All: |
3 reference(s)
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Analysis Tools
