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| Nomenclature |
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Symbol:
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Tg(SFTPC-EML4/ALK)502-4Hima
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Name:
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transgene insertion 502-4, Hiroyuki Mano
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MGI ID: |
MGI:3834680 |
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Synonyms: |
EML4-ALK |
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Transgene:
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Tg(SFTPC-EML4/ALK)502-4Hima
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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C57BL/6
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The promoter was used to drive lung-specific expression of a flag-tagged human fusion generated in human non-small-cell lung cancer due to recurrent chromosome inversion, inv(2)(p21p23). Two lines were created (502-4 and 501-3) that exhibit identical tumor-forming activity. Line 502-4 was selected as the representative line.
(J:142679)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:142679
Soda M et al.,
"A mouse model for EML4-ALK-positive lung cancer."
Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19893-7
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All: |
2 reference(s)
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Analysis Tools
