|
|
| Nomenclature |
|
Symbol:
|
Tg(Thy1-MAPT*K369I)K3Gotz
|
|
Name:
|
transgene insertion K3, Jurgen Gotz
|
|
MGI ID: |
MGI:3833383 |
|
Synonyms: |
K3 |
|
Transgene:
|
Tg(Thy1-MAPT*K369I)K3Gotz
Location:
unknown
|
|
Transgene
origin |
|
Strain of Origin:
|
(C57BL/6 x DBA/2)F2
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The promoter was used to drive neuron-specific expression of a mutated human cDNA lacking exon 3, containing four microtubule binding domains, and nucleotide substitutions that result in an amino acid substitution of isoleucine for lysine at position 369 (K369). One line was created (K3). (J:143439)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:143439
Ittner LM et al.,
"Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia."
Proc Natl Acad Sci U S A 2008 Oct 14;105(41):15997-6002
|
|
All: |
3 reference(s)
|
|
Analysis Tools
