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| Nomenclature |
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Symbol:
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Pomgnt1tm1Stk
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Name:
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protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase;
targeted mutation 1, Shin'ichi Takeda
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MGI ID: |
MGI:3832592 |
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Synonyms: |
POMGnT1-deficient |
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Gene:
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Pomgnt1
Location:
Chr4:116123840-116159849 bp, + strand
Genetic Position: Chr4,
53.1 cM, cytoband C7
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:144928
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 18 was replaced with a neo cassette. The absence of protein activity was confirmed by enzymatic assay and the lack of the glycosylated alpha-dystroglycan super moiety in western blot analysis. (J:144928)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pomgnt1 Mutation:
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28 strains or lines available |
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| References |
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Original: |
J:144928
Miyagoe-Suzuki Y et al.,
"Reduced proliferative activity of primary POMGnT1-null myoblasts in vitro."
Mech Dev 2008 Dec 16;():
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All: |
4 reference(s)
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Analysis Tools
