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| Nomenclature |
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Symbol:
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Slc6a3tm2(tTA)Xz
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Name:
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solute carrier family 6 (neurotransmitter transporter, dopamine), member 3;
targeted mutation 2, Xiaoxi Zhuang
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MGI ID: |
MGI:3832286 |
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Synonyms: |
DAT-tTA |
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Gene:
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Slc6a3
Location:
Chr13:73536747-73578672 bp, + strand
Genetic Position: Chr13,
40.1 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:144671
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A tetracycline responsive transactivator and a floxed neo cassette were inserted into the 5' untranslated region. Germ line, cre-mediated recombination was used to remove the neo cassette. Expression is limited in dopaminergic neurons. (J:144671)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Slc6a3 Mutation:
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32 strains or lines available |
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| References |
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Original: |
J:144671
Cagniard B et al.,
"Dopamine scales performance in the absence of new learning."
Neuron 2006 Sep 7;51(5):541-7
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All: |
2 reference(s)
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Analysis Tools
