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| Nomenclature |
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Symbol:
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Tg(H2-K-Fosl2,EGFP)13Wag
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Name:
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transgene insertion 13, Erwin F Wagner
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MGI ID: |
MGI:3813493 |
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Synonyms: |
fra-2tg |
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Transgene:
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Tg(H2-K-Fosl2,EGFP)13Wag
Location:
unknown
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Transgene origin |
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Strain of Origin:
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C57BL/6 x CBA
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The ubiquitous H2-Kb promoter was used to drive expression of the cDNA encoding Fosl2 followed by an IRES-EGFP. Three founders were identified (12, 13 and 15). Lines 12 and 13 display the same phenotype while founder 15 failed to express the transgene. Line 13 was used in subsequent analysis.
(J:139032)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:139032
Eferl R et al.,
"Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1."
Proc Natl Acad Sci U S A 2008 Jul 29;105(30):10525-30
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All: |
4 reference(s)
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