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| Nomenclature |
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Symbol:
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Itgavtm1Blb
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Name:
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integrin alpha V;
targeted mutation 1, Bernhard L Bader
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MGI ID: |
MGI:3790236 |
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Synonyms: |
alphavflox |
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Gene:
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Itgav
Location:
Chr2:83724397-83806916 bp, + strand
Genetic Position: Chr2,
49.33 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:134784
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 1. Transient flp expression in ES cells was used to remove the neo cassette leaving exon 1 floxed. (J:134784)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Itgav Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:134784
Lammermann T et al.,
"Rapid leukocyte migration by integrin-independent flowing and squeezing."
Nature 2008 May 1;453(7191):51-5
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All: |
2 reference(s)
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Analysis Tools
