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| Nomenclature |
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Symbol:
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Pscatm1Witt
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Name:
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prostate stem cell antigen;
targeted mutation 1, Owen N Witte
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MGI ID: |
MGI:3784994 |
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Gene:
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Psca
Location:
Chr15:74714839-74717063 bp, + strand
Genetic Position: Chr15,
34.26 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:133908
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: All of exon 2 and a portion of exon 3 were replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR from prostate and bladder extracts. (J:133908)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:133908
Moore ML et al.,
"Deletion of PSCA increases metastasis of TRAMP-induced prostate tumors without altering primary tumor formation."
Prostate 2008 Feb 1;68(2):139-51
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All: |
1 reference(s)
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Analysis Tools
