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| Nomenclature |
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Symbol:
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Mfsd7btm1.1Jlab
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Name:
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major facilitator superfamily domain containing 7B;
targeted mutation 1.1, Janis L Abkowitz
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MGI ID: |
MGI:3776022 |
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Gene:
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Mfsd7b
Location:
Chr1:191005832-191026190 bp, - strand
Genetic Position: Chr1,
96.28 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:132057
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exon 3 was removed by transient cre-mediated recombination. This is a functionally null allele because when an identical allele is cloned into NRK cells they fail to export ZnMP. (J:132057)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mfsd7b Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:132057
Keel SB et al.,
"A heme export protein is required for red blood cell differentiation and iron homeostasis."
Science 2008 Feb 8;319(5864):825-8
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All: |
1 reference(s)
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Analysis Tools
