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| Nomenclature |
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Symbol:
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Mmp16tm1Khol
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Name:
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matrix metallopeptidase 16;
targeted mutation 1, Kenn Holmbeck
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MGI ID: |
MGI:3771975 |
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Synonyms: |
mt3-mmp- |
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Gene:
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Mmp16
Location:
Chr4:17852893-18119145 bp, + strand
Genetic Position: Chr4,
7.08 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:130212
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Parent Cell Line:
| W4 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Exon 1 was replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR. (J:130212)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Mmp16 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:130212
Shi J et al.,
"Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis."
Dev Biol 2008 Jan 1;313(1):196-209
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All: |
2 reference(s)
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