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Mmp16tm1Khol
Targeted Allele Detail

Nomenclature
Symbol: Mmp16tm1Khol
Name: matrix metallopeptidase 16; targeted mutation 1, Kenn Holmbeck
MGI ID: MGI:3771975
Synonyms: mt3-mmp-
Gene: Mmp16   Location: Chr4:17852893-18119145 bp, + strand    Genetic Position: Chr4, 7.08 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:130212
Parent Cell Line: W4 (ES Cell)
Strain of Origin: 129S6/SvEvTac
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    Exon 1 was replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR. (J:130212)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mmp16 Mutation: 3 strains or lines available
References
Original: J:130212 Shi J et al., "Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis." Dev Biol 2008 Jan 1;313(1):196-209
All: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory