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| Nomenclature |
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Symbol:
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Slc40a1tm2Nca
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Name:
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solute carrier family 40 (iron-regulated transporter), member 1;
targeted mutation 2, Nancy C Andrews
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MGI ID: |
MGI:3771548 |
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Synonyms: |
Ferroportinflox, Fpnflox |
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Gene:
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Slc40a1
Location:
Chr1:45908070-45925594 bp, - strand
Genetic Position: Chr1,
23.96 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:129846
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo-cassette was inserted in intron 5 and a third loxP site was inserted in intron 7 via homologous recombination. The floxed neo cassette was removed by in vivo cre-mediated recombination leaving exons 6 and 7 flanked by loxP sites. (J:129846)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:129846
Donovan A et al.,
"The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis."
Cell Metab 2005 Mar;1(3):191-200
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All: |
6 reference(s)
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Analysis Tools
