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| Nomenclature |
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Symbol:
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Dlgap3tm1Gfng
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Name:
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discs, large (Drosophila) homolog-associated protein 3;
targeted mutation 1, Guoping Feng
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MGI ID: |
MGI:3759300 |
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Synonyms: |
Sapap3- |
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Gene:
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Dlgap3
Location:
Chr4:127169204-127237022 bp, + strand
Genetic Position: Chr4,
61.33 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:125181
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 3 containing the translation initiation codon was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis of brain lysate and postsynaptic density fraction. (J:125181)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Dlgap3 Mutation:
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55 strains or lines available |
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| References |
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Original: |
J:125181
Welch JM et al.,
"Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice."
Nature 2007 Aug 23;448(7156):894-900
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All: |
3 reference(s)
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Analysis Tools
