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| Nomenclature |
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Symbol:
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Bchetm1Loc
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Name:
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butyrylcholinesterase;
targeted mutation 1, Oksana Lockridge
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MGI ID: |
MGI:3723049 |
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Synonyms: |
BChE-, BChE KO |
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Gene:
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Bche
Location:
Chr3:73635808-73708415 bp, - strand
Genetic Position: Chr3,
33.61 cM, cytoband E3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:124975
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: 891bp of the gene is replaced with a neomycin selection cassette, including 485bp from the 3' end of intron 1 and 406bp from the 5' end of exon 2. The region encoding the entire signal peptide, the translation start site, and the first 102 amino acids of the mature protein is deleted. (J:124975)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:124975
Li B et al.,
"Production of the butyrylcholinesterase knockout mouse."
J Mol Neurosci 2006;30(1-2):193-5
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All: |
4 reference(s)
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Analysis Tools
