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| Nomenclature |
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Symbol:
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Gt(ROSA)26Sortm2(SS18)Mrc
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Name:
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gene trap ROSA 26, Philippe Soriano;
targeted mutation 2, Mario R Capecchi
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MGI ID: |
MGI:3710095 |
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Synonyms: |
SSM1 |
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Gene:
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Gt(ROSA)26Sor
Location:
Chr6:113067428-113077333 bp, - strand
Genetic Position: Chr6,
52.73 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:120967
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was designed to insert human synovial sarcoma translocation, chromosome 18, (SS18) into the locus. The vector also contained a strong transcriptional termination signal, NeoPA, flanked by loxP sites, such that the inserted cDNA is not transcribed without the presence of cre recombinase. (J:120967)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gt(ROSA)26Sor Mutation:
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196 strains or lines available |
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| References |
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Original: |
J:120967
Haldar M et al.,
"A conditional mouse model of synovial sarcoma: insights into a myogenic origin."
Cancer Cell 2007 Apr;11(4):375-88
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All: |
2 reference(s)
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