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| Nomenclature |
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Symbol:
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Smad4tm1Rdp
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Name:
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SMAD family member 4;
targeted mutation 1, Ronald DePinho
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MGI ID: |
MGI:3693621 |
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Synonyms: |
Smad4L |
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Gene:
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Smad4
Location:
Chr18:73639009-73703780 bp, - strand
Genetic Position: Chr18,
49.51 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:116130
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S/SvEv
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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LoxP sites were inserted to flank exons 8 and 9. (J:116130)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Smad4 Mutation:
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12 strains or lines available |
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| References |
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Original: |
J:116130
Bardeesy N et al.,
"Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer."
Genes Dev 2006 Nov 15;20(22):3130-46
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All: |
3 reference(s)
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Analysis Tools
