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| Nomenclature |
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Symbol:
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Gbatm1.1Karl
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Name:
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glucosidase, beta, acid;
targeted mutation 1.1, Stefan Karlsson
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MGI ID: |
MGI:3687966 |
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Synonyms: |
GCnull |
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Gene:
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Gba
Location:
Chr3:89202928-89208681 bp, + strand
Genetic Position: Chr3,
39.01 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:113751
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Exons 9-11 were removed via cre mediated recombination in ES cells. (J:113751)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gba Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:113751
Enquist IB et al.,
"Effective cell and gene therapy in a murine model of Gaucher disease."
Proc Natl Acad Sci U S A 2006 Sep 12;103(37):13819-24
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All: |
2 reference(s)
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Analysis Tools
