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| Nomenclature |
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Symbol:
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Coro1atm1Achn
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Name:
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coronin, actin binding protein 1A;
targeted mutation 1, Andrew C Chan
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MGI ID: |
MGI:3664599 |
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Synonyms: |
coronin 1- |
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Gene:
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Coro1a
Location:
Chr7:126699773-126707787 bp, - strand
Genetic Position: Chr7,
69.25 cM, cytoband F3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:111593
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 2 through 10 were replaced with a neomycin resistance cassette. No Coro1a protein was detected in thymocytes, splenocytes, or bone marrow-derived cells. (J:111593)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Coro1a Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:111593
Foger N et al.,
"Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis."
Science 2006 Aug 11;313(5788):839-42
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All: |
4 reference(s)
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Analysis Tools
