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| Nomenclature |
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Symbol:
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Adam33tm1.1Chch
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Name:
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a disintegrin and metallopeptidase domain 33;
targeted mutation 1.1, Chun Chen
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MGI ID: |
MGI:3664558 |
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Synonyms: |
ADAM33- |
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Gene:
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Adam33
Location:
Chr2:131050591-131063814 bp, - strand
Genetic Position: Chr2,
63.26 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:112306
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Parent Cell Line:
| RF8 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: The floxed exon 1 and neomycin resistance gene in Adam 33tm1Chch were removed via cre mediated recombination by mating with Tg(Tek-cre)1Rwng mice. Successful gene disruption was demonstrated by QRT-PCR, however LacZ expression was not detected.(J:112306)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Adam33 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:112306
Chen C et al.,
"ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice."
Mol Cell Biol 2006 Sep;26(18):6950-6
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All: |
1 reference(s)
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Analysis Tools
