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| Nomenclature |
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Symbol:
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Htr2atm1Grch
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Name:
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5-hydroxytryptamine (serotonin) receptor 2A;
targeted mutation 1, Jay A Gingrich
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MGI ID: |
MGI:3653429 |
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Synonyms: |
htr2a- |
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Gene:
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Htr2a
Location:
Chr14:74640840-74706859 bp, + strand
Genetic Position: Chr14,
39.37 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:110958
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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A floxed neomycin resistance gene-stop cassette was inserted into the 5' UTR to block transcription. (J:110958)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Htr2a Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:110958
Weisstaub NV et al.,
"Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice."
Science 2006 Jul 28;313(5786):536-40
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All: |
3 reference(s)
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Analysis Tools
