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| Nomenclature |
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Symbol:
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Prdm9tm1Ymat
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Name:
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PR domain containing 9;
targeted mutation 1, Yasuhisa Matsui
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MGI ID: |
MGI:3623909 |
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Synonyms: |
Meisetz- |
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Gene:
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Prdm9
Location:
Chr17:15545119-15564354 bp, - strand
Genetic Position: Chr17,
8.95 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:102875
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A targeting vector containing the lacZ gene and a loxP-flanked PGKneo cassette disrupted part of exon 2, which contains the initiation codon, all of exons 3 to 6, and part of exon 7. RT-PCR analysis of testes from homozygous mutant mice did not detect transcript. (J:102875)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:102875
Hayashi K et al.,
"A histone H3 methyltransferase controls epigenetic events required for meiotic prophase."
Nature 2005 Nov 17;438(7066):374-8
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All: |
4 reference(s)
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