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| Nomenclature |
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Symbol:
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Calcrltm1Kmca
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Name:
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calcitonin receptor-like;
targeted mutation 1, Kathleen M Caron
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MGI ID: |
MGI:3623122 |
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Synonyms: |
Calcrl- |
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Gene:
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Calcrl
Location:
Chr2:84330626-84425411 bp, - strand
Genetic Position: Chr2,
49.38 cM
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Generalized edema in Calcrltm1Kmca/Calcrltm1Kmca, Admtm1Unc/Admtm1Unc, and Ramp2tm1Kmca/Ramp2tm1Kmca mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:106927
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced exons 5 and 6, which includes the translation site, via homologous recombination. Quantitative RT-PCR confirmed absence of RNA. (J:106927)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Calcrl Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:106927
Dackor RT et al.,
"Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene."
Mol Cell Biol 2006 Apr;26(7):2511-8
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All: |
2 reference(s)
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Analysis Tools
