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| Nomenclature |
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Symbol:
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Rae1tm1Jvd
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Name:
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RAE1 RNA export 1 homolog (S. pombe);
targeted mutation 1, Jan M A van Deursen
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MGI ID: |
MGI:3619246 |
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Synonyms: |
Rae1- |
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Gene:
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Rae1
Location:
Chr2:173000117-173015739 bp, + strand
Genetic Position: Chr2,
95.66 cM
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Reduced lifespan, cataract, lordokyphosis and cachexia in Bub3tm1Jvd/Bub3+ Rae1tm1Jvd/Rae1+ mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:81546
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was designed to insert a promoterless IRES-lacZ-neo to interrupt the coding sequence at amino acid 50. (J:81546)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rae1 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:81546
Babu JR et al.,
"Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation."
J Cell Biol 2003 Feb 3;160(3):341-53
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All: |
3 reference(s)
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Analysis Tools
