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| Nomenclature |
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Symbol:
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Artm4(AR)Dmr
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Name:
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androgen receptor;
targeted mutation 1, Andrew P Lieberman
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MGI ID: |
MGI:3612537 |
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Synonyms: |
AR113Q, Artm1Apl |
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Gene:
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Ar
Location:
ChrX:98149721-98323215 bp, + strand
Genetic Position: ChrX,
42.82 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:104360
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Part of exon 1 was replaced by human AR exon 1 sequence with 113 CAG repeats. (J:104360)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:104360
Yu Z et al.,
"Abnormalities of Germ Cell Maturation and Sertoli Cell Cytoskeleton in Androgen Receptor 113 CAG Knock-In Mice Reveal Toxic Effects of the Mutant Protein."
Am J Pathol 2006 Jan;168(1):195-204
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All: |
7 reference(s)
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