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| Nomenclature |
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Symbol:
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Pvrl1tm1Ytk
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Name:
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poliovirus receptor-related 1;
targeted mutation 1, Yoshimi Takai
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MGI ID: |
MGI:3605480 |
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Synonyms: |
nectin 1- |
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Gene:
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Pvrl1
Location:
Chr9:43744576-43807454 bp, + strand
Genetic Position: Chr9,
24.42 cM, cytoband B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101707
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A construct was designed to replace sequence in exon 2 encoding amino acids 26-143 with a neomycin resistance gene. Absence of protein was confirmed by Western blot. (J:101707)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:101707
Inagaki M et al.,
"Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development."
Development 2005 Apr;132(7):1525-37
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All: |
6 reference(s)
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Analysis Tools
